5-Fluorouracil and filtering surgery

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منابع مشابه

Five-year follow-up of the Fluorouracil Filtering Surgery Study.

PURPOSE To determine the efficacy and safety of subconjunctival 5- fluorouracil injections after trabeculectomy in patients with poor prognoses, to determine risk factors for surgical failure and to examine the relationship of intraocular pressure and visual function. METHODS In this multicenter clinical trial, 213 patients with previous cataract surgery or previous failed filtering surgery w...

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Needling revision with subconjunctival 5-fluorouracil in failing filtering blebs.

BACKGROUND 5-Fluorouracil, an antimetabolic agent, improves the success rate of trabeculectomies by inhibiting subconjunctival fibrosis. However, complications may be associated with early postoperative use. We investigated the outcome of needling revision with delayed subconjunctival 5-fluorouracil in failing filtering blebs after a trabeculectomy in patients with medically poorly controlled g...

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Epithelial Downgrowth after Intraocular Surgery Treated with Intracameral 5-Fluorouracil

Purpose. To present the clinical and histopathologic correlation of two cases of epithelial downgrowth (EDG) after prior intraocular surgery. Methods. Observational case reports. Results. We present two cases of EDG occurring after intraocular surgery. In both cases, after two anterior chamber injections of 5-fluorouracil (5FU), the area of EDG initially regressed. In Case 1, a limited area of ...

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Topical Tretinoin and 5-Fluorouracil in treatment of epidermal nevus

Background: Epidermal nevus is a common skin hamartoma. Its definite treatment is difficult and in most cases the disease has recurrence. Objective: Evaluation of topical tretinoin 0.05% and 5 Fluorouracil (5FU) 5% in the treatment of epidermal nevus. Patients and Methods: Fifteen patients with epidermal nevus referred to skin clinic in Razi Hospital in Tehran whose diagnoses were confirm...

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Effect of Skimmed Milk on the Absorption and Metabolism of 5-Fluorouracil (5-FU) in Animals

     Several modalities of drug administration have been investigated to improve bioavailability and to reduce 5-FU related toxicity. The aim of present study was to evaluate the effect of skimmed milk on the absorption and metabolism of 5-FU in rabbits, mice and dogs. It was further aimed to determine its route related toxicity in rabbits.    Plasma concentration of both 5-FU and its metabolit...

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ژورنال

عنوان ژورنال: Australian and New Zealand Journal of Ophthalmology

سال: 1991

ISSN: 0814-9763,1440-1606

DOI: 10.1111/j.1442-9071.1991.tb00655.x